Dylan Larkin scored to extend his point streak to 13 games for the Red Wings (15-19-6), who have lost four in a row and are 2-7-2 in their past 11 games. Jonathan Bernier made 37 saves.
"We deserved to lose, 100 percent," Detroit coach Jeff Blashill said. "We lost too many [pucks]. They were faster than us all over the ice. I do not think that they are faster than us, so that's the way we played. We have to be better than them."
Stars coach Jim Montgomery shuffled three of four forward lines, including breaking up the top line of Benn, Seguin and Radulov. The one line that he left intact from their 2-0 road win against the Nashville Predators on Thursday was Comeau, Faksa and Tyler Pitlick.
"It helps Pitlick's playing unreal right now," Montgomery said. "And Comeau is just a glue guy, and the three of them are playing really well. These last two games, if it wasn't for them, I don't know if we win the games. That's how they've played."
Seguin had an assist and won 12 of 20 face-offs. Benn had no points, two shots on goal and three blocked shots.
Montgomery said of them: "I thought they helped us win."
Comeau gave Dallas a 1-0 lead at 5:11 of the second period with a tap-in at the right side of the crease on the rush off a pass from Faksa near the left boards.
Radulov scored the next two goals. His wrist shot from the right face-off dot off a pass from Mattias Janmark gave Dallas a 2-0 lead at 11:11. At 14:43, he put in the rebound of a Spezza shot on the power play to make it 3-0.