Columbus Blue Jackets at Buffalo Sabres (7 p.m. ET; MSG-B, BSOH, ESPN+, NHL LIVE)
Patrik Laine has scored two goals in three straight games for Columbus (21-22-1) and the forward has scored nine points (six goals, three assists) in his past four. He left practice early Wednesday because of an upper-body injury but could play after taking line rushes during the morning skate. Buffalo (14-24-7), which plays its first game since the All-Star break, has lost three of four, getting outscored 15-6.
Carolina Hurricanes at Boston Bruins (7 p.m. ET; NESN, BSSO, SN360, TVAS, ESPN+, NHL LIVE)
The Bruins (26-15-3) will be without center Patrice Bergeron (upper body) and forward Brad Marchand, who will serve the first of a six-game suspension from the NHL Department of Player Safety for high-sticking and roughing Penguins goalie Tristan Jarry on Tuesday. The Hurricanes (31-10-3) hope to avoid their third straight loss (0-1-1). They have allowed the fewest goals per game this season (2.41).
Pittsburgh Penguins at Ottawa Senators (7 p.m. ET; TSN5, RDS, ATTSN-PT, ESPN+, NHL LIVE)
The Penguins have won four of the past five games against the Senators, including 6-4 on Jan. 20. Ottawa seeks its third consecutive win after defeating Carolina 4-3 on Tuesday. Brady Tkachuk scored two goals for the Senators, ending a 15-game goal drought, and has scored five points (two goals, three assists) in his past four games.
Washington Capitals at Montreal Canadiens (7 p.m. ET; TSN2, RDS, NBCSWA, ESPN+, NHL LIVE)
Capitals coach Peter Laviolette is two wins from becoming the 10th coach in NHL history to win 700 games. His 698 wins are third among active coaches behind Barry Trotz (893) and Lindy Ruff (771). Canadiens forward Tyler Toffoli has scored eight points (four goals, four assists) in eight games after missing 11 following hand surgery.
New Jersey Devils at St. Louis Blues (8 p.m. ET; BSMW, MSG+2, ESPN+, NHL LIVE)
The Devils (16-26-5), who defeated the Canadiens 7-1 on Tuesday, seek consecutive wins for the first time since Dec. 31-Jan. 2. New Jersey is 6-15-2 on the road this season. St. Louis (26-13-5) forward Vladimir Tarasenko has a point in 11 of his past 12 games (seven goals, 10 assists). It's the Blues' first game since a 4-1 loss to the Winnipeg Jets on Jan. 29.
Toronto Maple Leafs at Calgary Flames (9 p.m. ET; SNW, TSN4, ESPN+, NHL LIVE)
Auston Matthews will be a game-time decision for the Maple Leafs (30-10-3) after the center was injured during a 4-3 overtime win against the Hurricanes on Monday. Toronto owns the longest-active winning streak in the NHL (six games) and forward Mitchell Marner will try to become the eighth player since 1990-91 to score a goal in nine consecutive games. The Flames (24-13-6) have won four in a row and play the second of a back-to-back set after a 6-0 win against the Vegas Golden Knights on Wednesday.
Tampa Bay Lightning at Colorado Avalanche (9 p.m. ET; ALT, BSSUN, ESPN+, NHL LIVE)
The Lightning are 7-2-1 in their past 10 games. Avalanche forward Mikko Rantanen has scored 14 points (eight goals, six assists) in his past 11 and forward Nazem Kadri has scored nine points (four goals, five assists) during a five-game point streak.