Ryan Reaves scored his first goal since March 20, 2020 and gave Vegas a 4-3 lead when he redirected Tomas Nosek's shot at 12:27. The Golden Knights are 5-0-0 against the Sharks this season.
"Any time you do anything against the Sharks, it's fun," Reaves said. "It's no secret I hate every one of them over there."
Shea Theodore had a goal and two assists, and Marc-Andre Fleury made 29 saves for the Golden Knights (20-6-1), who trailed 3-1 after the second period.
"I think our group has a confidence to what we do," Vegas coach Peter DeBoer said. "I think we've done it enough where we know that if we get a certain amount of pressure on the other team at the right moments in the third, we have the chance to grab that momentum."