However, the Lightning were able to notch the game at 1-1 at 13:56. Pat Maroon fired a shot from the high slot that made its way through heavy traffic in front of Greiss and into the back of the net.
Detroit outshot Tampa Bay, 12-9, in the middle frame, with the Red Wings' best chance coming from Zadina eight minutes into the period. But the Lightning scored the only goal of the frame, courtesy of a one-timer from Barclay Goodrow with 2:31 remaining to claim a 2-1 lead heading into the second intermission.
The Red Wings were held without a shot for the first nine minutes of the third period before Larkin fired a one-timer that required a cross-crease save from Lightning goaltender Andrei Vasilevskiy.
Tampa Bay put the game out of reach with an empty-net tally from Goodrow, his second of the night, with 28 seconds remaining. The victory was the Lightning's 16th straight over the Red Wings in Tampa Bay.
Larkin said the team can build on the effort shown on Friday night, but needs to find a way to better generate and capitalize offensively.
"Tonight was much better," Larkin said. "We're still not there yet, but it was a much better effort. If we play that way and improve on some small things, we're going to be successful our next games in Florida."
The Red Wings continue their six-game road trip and look to snap their eight-game winless streak (0-6-2) with a pair of games against the Florida Panthers on Sunday, Feb. 7 at 3 p.m. and Tuesday, Feb. 9 at 7 p.m.