Vinni Lettieri and Declan Chisholm scored, and Filip Gustavsson made 30 saves for Minnesota (36-30-9), which has lost two of three. The Avalanche completed a three-game, season series sweep against the Wild (0-2-1), outscoring them 10-5.
"I thought their goaltender was a big difference in the game," Wild coach John Hynes said. "I thought both goaltenders played well, but I thought their guy made a lot of key saves at key times. We had really good offensive pressure. Lots of good scoring opportunities, high quality opportunities in really all situations and couldn't find a way to get it in the back in the net."
Artturi Lehkonen put the Avalanche ahead 1-0 at 4:34 of the first period off a rebound after Gustavsson was unable to cover Jack Johnson's shot from the point.
Lettieri answered back and the Wild tied it 1-1 at 8:05 with a one-timer from the right circle off a behind-the-net pass from Mason Shaw.
"I thought we played well," Minnesota forward Matt Boldy said. "Obviously they're a really good team with some special players and you see that every time. You do what you can but they're good, and it's tough at times but I thought we played well. Just played our game, lot of chances, won battles, played fast; just have keep going."