Talbot stopped 31 shots and looked especially good through 40, but for the second straight night, the well ran dry and the Flames were shut out on the road.
This time, to the tune of 6-0 to the Vegas Golden Knights.
"It's getting pretty old," said Matthew Tkachuk, "It's not that our starts have been horrible, but we can't get this lead. Then we trail, they press, and put a six-spot up on us when it was a pretty tight game until the third period.
"I don't know what happened, but we let them run away with it. We've hung our goalie out to dry countless times and it's getting old.
"It's disgusting. It's bad, it's bad right now. We need to (turn) this around. Maybe going home for one game can do that, spark us going into that road trip, but something's got to change here and we have to get back to being the old us. Because this isn't fun right now."
With the loss, the Flames fall to 10-10-3 on the year.
Talbot was under siege early, facing five shots in the first two-and-a-half minutes, and turning them all aside as the Knights - losers of a franchise high, five straight entering the night - pressed for the icebreaker.
The Flames had a good response, but a couple of tough bounces one way burned the visitors and put them in a 1-0 hole approaching the midway mark of the period.
With Marc-Andre Fleury scrambling back into position, Sean Monahan had what looked to be an open net to shoot for, but William Karlsson came up with a clutch block to send the play back the other way in transition.
He who started it, finished it, as Karlsson looked off Max Pacioretty on a 2-on-1 and blazed a perfectly placed shot over the blocker, bar down, to put the Knights in front at 9:07.
Talbot, though, was dialled in and make a couple of great stops to keep his team in it late in the period. First, Mark Stone created a 2-on-1 similar to the Karlsson play, but he stuck out his left hand and got a piece of the sizzling wrister to glove it out of the rink.
Then, after coming up with a strong, positional save off Karlsson moments earlier, he snared a Pacioretty blast from the right circle with a windmill-like wave of the arm.
Shots on goal favoured the Flames 13-11 after one.
"It's hard to get it to go (offensively) in right now," said Head Coach Bill Peters. "Some big saves, obviously. But our guy was good, too. Our guy was good when the game was on the line."